Buhari, H.A., Sagir, A., Akuyam, S.A., Erhabor, O., Panti, A.A, Garba, N.
AJLHTS: Original Paper DOI – https://www.ajlhtsonline.org/doi-org-10-59708-ajlhts-v2i3-2330/
Abstract
Background: Blood group antigens have been used to evaluate ethnic
diversity of human populations and they also play most important
roles in pregnancy and blood transfusion. Knowledge of antigen
frequencies is important to assess the risk of alloimmunization and
to guide the probability of finding antigen-negative donor blood.
This study was aimed at determining the frequencies of ABO, Rh
and Kell blood group antigens phenotype among pregnant women.
Materials and Methods: The study was cross sectional in nature
conducted among 1,250 consecutively recruited pregnant women
in the department of Obstetrics and Gynaecology, antenatal clinic in
Sokoto from January 2020 to September 2020. The blood grouping
were determined using standard tube techniques for ABO while
column agglutination card was used for Rh C, E, c, e and Kell blood
groups. The data were collected, and calculations were done to
determine the frequencies of ABO, Rh, and Kell blood group antigens
and chi square was used to determine statistical significance .
Results: The distribution of the ABO blood group revealed that
48.5% were group O, 27.3% were group B, 19.4% were group A and
4.8% were group AB. Out the subjects investigated, 93.1%, 30.2%,
24.6% , 90.2% and 97.6%were RhD, RhC, RhE, Rhc and Rhe positive
respectively while 2.4% were Kell positive while 97.6% were Kell
negative. ABO antigens has statistically significant correlation with
Kell antigens.