Long-Lasting Antibody Responses in Covid-19: Natural Infection Versus Vaccination

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Article DOI: 10-59708-ajlhts-v4i1-2514

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ABSTRACT
Introduction: The COVID-19 pandemic caused by the SARS-CoV-2 virus was a devastating global occurrence that has prompted extensive efforts to diagnose and control its spread. Vaccination
eventually emerged as a key strategy to mitigate the impact of the virus, yet several questions emerged on the efficacy of the vaccination in sustaining immunity in infected and non-infected
subjects. There were also controversies that vaccination does not offer any advantage over herd immunity. This study was aimed at detecting the presence of SARS-CoV 2 Nucleocapsid IgM and IgG in vaccinated and unvaccinated subjects to bridge this knowledge gap.

Donor Health Monitoring: Strategies for Preventing Short- and Long-term Effects of Apheresis

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Article DOI: 10-59708-ajlhts-v4i1-2515

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ABSTRACT
Introduction: Apheresis is a vital procedure in transfusion medicine and therapeutic applications, enabling the collection of specific blood components or the therapeutic removal of pathological substances. While generally safe, apheresis presents notable challenges related to donor health, particularly in the context of repeated donations. Short-term complications, including hypocalcaemia, vasovagal reactions, and localised venous access issues, can cause immediate discomfort and procedural disruptions. Long-term effects, such as iron deficiency, bone density reduction, and potential immune dysregulation, also pose significant risks to frequent donors. Donor health monitoring is important in preventing these adverse effects by carrying out pre-donation screening, monitoring, and follow-up protocols. Despite these measures, challenges and research gaps remain, particularly concerning the long-term impacts of repeated
apheresis on donor immune function and overall health. This review explores evidence-based strategies to mitigate these effects,  and ensure donor safety while sustaining a reliable supply of blood products.

Evaluation of Coagulation Markers in Pregnant Women Attending Antenatal Care at a Teaching Hospital in Aba, Nigeria.

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Article DOI: 10-59708-ajlhts-v4i1-2517

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ABSTRACT
Introduction:
Pregnancy may alter the haemostatic system, which is directed at protecting the maternal subjects from haemorrhage during pregnancy and postpartum and the foetal subjects during
implantation. This study was set to investigate the effect of pregnancy on the haemostatic system and possible predisposition to coagulopathy.

Prevalence of Human Immunodeficiency Virus Infection in Pregnant Women Attending Traditional Birth Homes And Hospitals In Southern Nigeria

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DOI URL: 10.59708/ajlhts.v3i3.2426

 

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Abstract
Introduction:
Prevention of mother-to-child transmission is an important strategy for the control of human immunodeficiency virus (HIV) infection. While the structure for this intervention programme exists within conventional antenatal care, infected pregnant women  who prefer the services of traditional birth attendants (TBAs) could be at risk of being undetected. This study aimed to evaluate the prevalence of HIV infection among pregnant women accessing antenatal care across conventional health facilities and traditional birth homes (TBHs) in Uyo, southern Nigeria.

Distribution of ABO/Rh Blood Groups and Haemoglobin Phenotypes among University Students in South-West, Nigeria.

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DOI URL: 10.59708/ajlhts.v3i3.2431

 

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ABSTRACT
Background:
Assessing university students’ blood group and hemoglobin phenotypes is vital for health policies, and premarital counseling. This study aimed at determining the distribution of Blood group and hemoglobin phenotype among university students in Southwest Nigeria

Effect of Hydroxyurea Therapy on Markers of Inflammation and Clinical Variability of Sickle Cell Anaemia; A Prospective Study at a Missionary Hospital

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DOI URL: 10.59708/ajlhts. v3i3.2432

 

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Abstract
Background: Immune mediators of inflammation are implicated in the pathophysiological processes and clinical variability of sickle
cell anaemia (SCA). This study determined the effect of hydroxy-urea therapy on markers of inflammation and clinical variability of sickle cell anaemia in Ghana.

Gray Hair And Haematology: A Union of Deficiency

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DOI URL: 110.59708/ajlhts. v3i3.2434

 

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SUMMARY
Graying of hair is one inevitable condition of life; gray hair can start appearing on one’s head or other parts of the body at one time or another, but if one lives till he or she is old, it must appear. Hair gets gray when the production of melanin, the chemical that gives hair its colour, is reduced or stopped for any of the follicles; the new hair that will grow out will no longer have color. Usually, graying comes
with old age, but sometimes it starts early in some individuals based on their genes or other conditions.

Correlation of Haemoglobin and Haematocrit with Hepatitis C Infection Among Patients Undergoing Hemodialysis in a Tertiary Hospital in Ogun State, Nigeria

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DOI URL: 10.59708/ajlhts. v3i3.2435

 

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ABSTRACT
Background: The Hepatitis C Virus (HCV) is a major cause ofmorbidity among patients with chronic kidney disease undergoing hemodialysis. This study investigates the correlation between hemoglobin (Hb), hematocrit (HCT), and HCV infection in
these patients, aiming to provide insights into the hematological implications of HCV in hemodialysis patients.

Phagocytic Functions of Peripheral Blood Neutrophil In Subjects with Leukaemia

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DOI URL: 10.59708/ajlhts.v3i3.abs.1

 

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Abstract
Background: An efficient immune system is crucial for the host to mount a sufficient immune response, particularly in times of disease and traumatic injury. In leukaemia, regardless of the type, the abnormal cells in the bone marrow suppress the formation of other cells, leading to several adverse effects. Our research suggests that the traditional innate immune functions of neutrophils might be impaired in subjects with leukaemia, which could have significant implications for the immune system’s response to disease and injury.