doi-org-10-59708-ajlhts-v3i2-2415
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Abstract
Atypical chronic myeloid leukemia (aCML) is a rare form of myelodysplastic syndrome/myeloproliferative neoplasm. This report
presents a case of aCML in a 75-year-old man, diagnosed based on
cytologic evidence of neutrophilia, presence of neutrophil precursors, thrombocytopenia on complete blood count and microscopy,
and granular hyperplasia and dysgranulopoiesis on myelogram.
The patient was in good clinical condition with isolated splenomegaly. With hydroxyurea, the hyperleukocytosis was controlled, and
the splenomegaly disappeared. The lymphadenopathy identified
on a CT scan led to the diagnosis of prostate cancer, while the general health condition of the patient was impairing.
Key words: atypical chronic myeloid leukemia; prostate cancer;
hydroxyurea.