High pre-and post-treatment Platelet-Neutrophil to Lymphocyte ratio is linked to high mortality risk in Epithelial Ovarian Cancer patients in Southeastern Nigeri


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Introduction: To identify risk factors and prognostic tools for
epithelial ovarian cancer (EOC), an aggressive ovarian cancer, this
study assessed the frequency of BRCA2 mutation in early-onset (≤
50 years old) and late-onset (> 50 years old) EOC and variation of
systemic immune-inflammatory indices, especially among herbal
medicine- and chemotherapy-experienced patients.
Methods: This study included 100 patients diagnosed with EOC
from Jan. 2016 to Dec. 2021. The neutrophil-to-lymphocyte ratio
(NLR), platelet-to-lymphocyte ratio (PLR), platelets-neutrophilsto-lymphocytes ratio (PNLR), and neutrophils-to-lymphocytes
platelets ratio (NLPR) were assessed and analyzed accordingly.
Significance was set at p< 0.05.

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