Expression of BCL-2 and BAD Genes in Benzene-Induced Haematotoxicity Bearing Wistar Rats Treated with Bi- Herbal Formula of Picralima Nitida and Cymbopogon Citratus Extract

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Article DOI: 10-59708-ajlhts-v4i2-2520

 

ABSTRACT

Background: Picralima nitida and Cymbopogon citratus, traditionally used in West Africa, have gained interest for their potential health benefits. P. nitida shows antioxidant and anti-diabetic properties, while C. citratus exhibits anti-inflammatory and antioxidant effects. There is a need to study their ability to protect against benzene induced blood toxicity, potentially by influencing BCL-2 and BAD gene expression. This study aimed to evaluate the effects of aqueous leaf extracts from P. nitida and C. citratus on BCL-2 and BAD gene expression in rats with benzene-induced blood toxicity in albino Wistar rats.

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